ATRACURIUM BESYLATE Meaning and
Definition
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Atracurium Besylate is a medication classified as a non-depolarizing neuromuscular blocking agent. It is used primarily in anesthesia to induce muscle relaxation. Atracurium Besylate belongs to a class of drugs known as benzylisoquinolinium compounds.
When administered intravenously, Atracurium Besylate acts by competitively binding to the nicotinic acetylcholine receptors (nAChRs) found on the motor endplate of skeletal muscle cells. By blocking the binding of acetylcholine, a neurotransmitter responsible for muscle contraction, Atracurium Besylate prevents communication between nerve impulses and the muscles. This results in temporary paralysis and muscle relaxation.
Atracurium Besylate is considered an intermediate-acting neuromuscular blocking agent, with an onset of action within 2-4 minutes and a duration of effect lasting approximately 30-40 minutes. It is advantageous in surgical procedures that require prolonged relaxation and muscle paralysis, such as abdominal surgeries or endotracheal intubation.
The drug is typically administered intravenously by a healthcare professional and its dosage is individualized based on factors such as patient age, weight, and the desired level of muscle relaxation. Atracurium Besylate is metabolized by the body through a process called Hoffmann elimination, which is independent of renal or hepatic function.
Though generally well-tolerated, Atracurium Besylate may cause side effects such as hypotension (low blood pressure), bronchospasm (narrowing of the airways), histamine release, and prolonged neuromuscular blockade. As with any medication, it is important to follow the prescribed dosage and consult
Common Misspellings for ATRACURIUM BESYLATE
- ztracurium besylate
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Etymology of ATRACURIUM BESYLATE
The word "Atracurium" is a combination of "Atra-" derived from "Atrax", which is the genus name of a venomous spider found in Australia, and "-curium" derived from "curare", a neurotoxin used in traditional South American medicine. The word "Besylate" is derived from "benzenesulfonic acid", an organic compound, and "-ate", a suffix commonly used in chemistry to indicate a salt. Therefore, "Atracurium Besylate" refers to a salt form of the compound Atracurium that contains a besylate ion.
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