RYANODINE Meaning and
Definition
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Ryanodine is a chemical compound that belongs to the alkaloid class of naturally occurring substances. It is derived from the Ryania speciosa plant and has a unique structure that contains a large lactone ring system.
In a physiological context, Ryanodine acts as a potent and selective inhibitor of the ryanodine receptor (RyR), a type of calcium channel present in muscle cells. RyRs are responsible for releasing calcium ions from the sarcoplasmic reticulum, a specialized cellular organelle, into the cytoplasm during muscle contraction. By binding to the RyR, Ryanodine disrupts the normal calcium release mechanism, inhibiting the flow of calcium ions and subsequently affecting muscle function.
Furthermore, Ryanodine has been extensively studied and utilized pharmacologically due to its potential therapeutic applications. It has shown promise in treating certain cardiac arrhythmias, such as ventricular tachycardia, by affecting calcium release and regulating heart rhythm. Additionally, Ryanodine has been used as a valuable tool in laboratory research to study intracellular calcium signaling and the mechanisms behind normal and abnormal muscle function.
However, it is important to note that Ryanodine is a highly toxic compound and can induce severe poisoning and adverse effects if ingested at high doses. Given its potency, caution and strict safety protocols must be observed when handling and using Ryanodine in both clinical and laboratory settings.
Common Misspellings for RYANODINE
- eyanodine
- dyanodine
- fyanodine
- tyanodine
- 5yanodine
- 4yanodine
- rtanodine
- rganodine
- rhanodine
- ruanodine
- r7anodine
- r6anodine
- ryznodine
- rysnodine
- rywnodine
- ryqnodine
- ryabodine
- ryamodine
- ryajodine
- ryahodine
Etymology of RYANODINE
The word "Ryanodine" comes from a combination of "Ryan" and "odine". "Ryan" is derived from the surname of Thomas F. Ryan, an American chemist who first discovered the compound in 1949 along with a team of researchers. The second part, "odine", derives from "alkaloid", which refers to naturally occurring compounds that have basic nitrogen atoms and are often found in plants. Hence, the term "Ryanodine" represents the alkaloid compound discovered by Thomas F. Ryan.
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