RENIN ANGIOTENSIN SYSTEM Meaning and
Definition
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The Renin-Angiotensin System (RAS) is a vital hormonal system in the human body that plays a significant role in maintaining blood pressure and fluid balance. It regulates the volume of extracellular fluid and arterial vasoconstriction/dilation by controlling the synthesis and release of hormones and enzymes.
The RAS begins with the production of renin, an enzyme released by the kidneys when blood pressure drops or fluid volume decreases. Renin acts on angiotensinogen, a protein produced in the liver, to form angiotensin I. Angiotensin I is then converted into angiotensin II by the enzyme angiotensin-converting enzyme (ACE), primarily found in the lungs.
Angiotensin II is a potent vasoconstrictor, causing blood vessels to narrow and increasing peripheral resistance. It also stimulates the release of aldosterone from the adrenal cortex, which promotes the reabsorption of sodium in the kidneys and increases blood volume. Furthermore, angiotensin II stimulates the release of antidiuretic hormone (ADH) from the pituitary gland, which reduces water loss through urine.
Overall, the activation of the Renin-Angiotensin System in response to low blood pressure or decreased fluid volume helps restore blood pressure by increasing vascular tone, promoting salt and water retention, and reducing water loss. However, in cases of chronic activation or dysregulation of the RAS, it can contribute to the development of cardiovascular diseases such as hypertension and heart failure.
Common Misspellings for RENIN ANGIOTENSIN SYSTEM
- eenin angiotensin system
- denin angiotensin system
- fenin angiotensin system
- tenin angiotensin system
- 5enin angiotensin system
- 4enin angiotensin system
- rwnin angiotensin system
- rsnin angiotensin system
- rdnin angiotensin system
- rrnin angiotensin system
- r4nin angiotensin system
- r3nin angiotensin system
- rebin angiotensin system
- remin angiotensin system
- rejin angiotensin system
- rehin angiotensin system
- renun angiotensin system
- renjn angiotensin system
- renkn angiotensin system
- renon angiotensin system
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