NEUROTROPHIC PROTEIN Meaning and
Definition
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Neurotrophic proteins are a group of specialized molecules that play a crucial role in promoting the growth, development, and survival of neurons (nerve cells) in the central nervous system (CNS) and peripheral nervous system (PNS). These proteins act as chemical messengers or growth factors that regulate various processes involved in neuronal growth, regeneration, and maintenance.
Neurotrophic proteins function by binding to specific receptors on the surface of neurons, activating intracellular signaling pathways that ultimately lead to cellular responses. They assist in the formation of new neuronal connections, promote the differentiation of neural stem cells into mature neurons, and enhance the survival and maintenance of existing neurons.
One of the most well-known neurotrophic proteins is nerve growth factor (NGF), discovered by Rita Levi-Montalcini and Stanley Cohen. NGF stimulates the growth and survival of sympathetic and sensory neurons. Other essential neurotrophic proteins include brain-derived neurotrophic factor (BDNF), glial cell line-derived neurotrophic factor (GDNF), and neurotrophin-3 (NT-3).
Impairments or deficiencies of neurotrophic proteins have been associated with various neurological disorders, including Alzheimer's disease, Parkinson's disease, and amyotrophic lateral sclerosis (ALS). Additionally, research has shown the potential therapeutic application of neurotrophic proteins in promoting neuronal regeneration and recovery after injury or disease.
In summary, neurotrophic proteins are essential molecular factors that facilitate the growth, differentiation, and survival of neurons in the nervous system. Their pivotal role in neural development and repair makes them a valuable area of study for understanding and treating various neurological conditions.
Common Misspellings for NEUROTROPHIC PROTEIN
- beurotrophic protein
- meurotrophic protein
- jeurotrophic protein
- heurotrophic protein
- nwurotrophic protein
- nsurotrophic protein
- ndurotrophic protein
- nrurotrophic protein
- n4urotrophic protein
- n3urotrophic protein
- neyrotrophic protein
- nehrotrophic protein
- nejrotrophic protein
- neirotrophic protein
- ne8rotrophic protein
- ne7rotrophic protein
- neueotrophic protein
- neudotrophic protein
- neufotrophic protein
- neutotrophic protein
Etymology of NEUROTROPHIC PROTEIN
The word "neurotrophic" is derived from the combination of two words: "neuro" meaning "related to nerves" and "trophic" meaning "relating to nutrition or growth".
The term "protein" originates from the Greek word "proteios", meaning "primary" or "standing in front". In biology, proteins are essential macromolecules that play a crucial role in various cellular activities and structures.
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