How Do You Spell LYSYL TRNA SYNTHETASE?

1. Lysyl tRNA Synthetase is an enzyme that plays a crucial role in protein synthesis, specifically in the process of translation. It is classified as a specific aminoacyl-tRNA synthetase, which is responsible for attaching the correct amino acid to its corresponding tRNA molecule, ensuring the accurate incorporation of amino acids during protein synthesis.

   The function of Lysyl tRNA Synthetase is to specifically attach the amino acid lysine to the appropriate tRNA molecule, forming a charged tRNA-Lys complex. This complex is then recognized by ribosomes during translation to properly incorporate lysine into the growing polypeptide chain.

   The enzyme achieves this through a two-step reaction process. In the first step, Lysyl tRNA Synthetase activates the amino acid lysine by attaching it to adenosine triphosphate (ATP), forming a high-energy intermediate called aminoacyl-AMP. In the second step, the enzyme transfers the activated lysine molecule from aminoacyl-AMP to the specific tRNA molecule designed for lysine, known as tRNA-Lys. This reaction results in the formation of a charged tRNA-Lys complex.

   Lysyl tRNA Synthetase is essential for accurate protein synthesis, as errors in charging tRNA molecules with incorrect amino acids can result in misincorporation of amino acids during translation, leading to dysfunctional proteins. Therefore, the precise activity of this enzyme is critical for maintaining the integrity and functionality of the cellular proteome.

Common Misspellings for LYSYL TRNA SYNTHETASE