GAMMA GLUTAMYLAMINE CYCLOTRANSFERASE Meaning and
Definition
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Gamma glutamylamine cyclotransferase is an enzyme that plays a crucial role in the metabolism of substances within an organism. It belongs to the class of transferases, which are enzymes that facilitate the transfer of functional groups between molecules. Specifically, gamma glutamylamine cyclotransferase catalyzes the cyclization of gamma glutamylamines, resulting in the formation of a cyclic product.
The enzyme is involved in a metabolic pathway known as the gamma glutamyl cycle, which is important for the detoxification of certain compounds, particularly glutathione, a key antioxidant in cells. Gamma glutamylamine cyclotransferase aids in the breakdown of gamma glutamylamines, which are byproducts of the gamma glutamyl cycle. This process allows for the regeneration of glutathione and the efficient elimination of potentially harmful substances.
The activity of gamma glutamylamine cyclotransferase is dependent on the presence of various cofactors, including pyridoxal 5'-phosphate, which is derived from vitamin B6. The enzyme is found in various tissues throughout the body, including the liver, kidney, and gastrointestinal tract.
The proper functioning of gamma glutamylamine cyclotransferase is crucial for maintaining overall metabolic balance and preventing the accumulation of toxic substances. Dysregulation or deficiencies in this enzyme can lead to disruptions in the gamma glutamyl cycle, potentially resulting in cellular damage and disease states.
Common Misspellings for GAMMA GLUTAMYLAMINE CYCLOTRANSFERASE
- famma glutamylamine cyclotransferase
- vamma glutamylamine cyclotransferase
- bamma glutamylamine cyclotransferase
- hamma glutamylamine cyclotransferase
- yamma glutamylamine cyclotransferase
- tamma glutamylamine cyclotransferase
- gzmma glutamylamine cyclotransferase
- gsmma glutamylamine cyclotransferase
- gwmma glutamylamine cyclotransferase
- gqmma glutamylamine cyclotransferase
- ganma glutamylamine cyclotransferase
- gakma glutamylamine cyclotransferase
- gajma glutamylamine cyclotransferase
- gamna glutamylamine cyclotransferase
- gamka glutamylamine cyclotransferase
- gamja glutamylamine cyclotransferase
- gammz glutamylamine cyclotransferase
- gamms glutamylamine cyclotransferase
- gammw glutamylamine cyclotransferase
- gammq glutamylamine cyclotransferase
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