How Do You Spell CONTACT HYPERSENSITIVITY?

1. Contact hypersensitivity is a specific type of allergic reaction that occurs when the immune system becomes sensitized to a substance after repeated direct contact with it. It is characterized by an exaggerated response of the immune system upon re-exposure to the substance, resulting in a localized inflammatory reaction. This condition is often seen in individuals who are susceptible to allergies.

   Contact hypersensitivity typically manifests as a red, itchy rash or blisters on the skin at the site of contact with the allergen. Common triggers include certain metals, such as nickel or gold, cosmetics, fragrances, latex, plants like poison ivy or poison oak, and various chemicals used in industrial or household products. Unlike immediate allergic reactions, the symptoms of contact hypersensitivity may take hours or even days to develop after contact with the allergen.

   Mechanistically, contact hypersensitivity involves two phases: the sensitization phase and the elicitation phase. During sensitization, the immune system recognizes the allergen as foreign and produces specific immune cells called T-lymphocytes. Upon subsequent exposure, the elicitation phase occurs, in which these sensitized T-lymphocytes release inflammatory mediators, causing the characteristic symptoms of the allergic reaction.

   Treatment for contact hypersensitivity aims to provide relief from symptoms and prevent further exposure to the triggering allergen. Topical corticosteroids, antihistamines, and moisturizers may be recommended to alleviate itching and inflammation. In severe cases, systemic corticosteroids or immune-modulating medications may be prescribed. Identifying and avoiding the specific allergen is crucial in managing contact hypersensitivity, and patch testing can help identify the substances to which an individual is allergic.

Common Misspellings for CONTACT HYPERSENSITIVITY

The term "Contact Hypersensitivity" can be broken down into two parts: "contact" and "hypersensitivity".

- "Contact" originated from the Latin word "contactus", which means "touch" or "connection". It entered the English language through the Old French word "contact" with the same meaning.

- "Hypersensitivity" is formed by combining the prefix "hyper-" meaning "excessive" or "over", and "sensitivity" which comes from the Latin word "sensibilitas" meaning "responsiveness to stimuli". The term "hypersensitivity" refers to an exaggerated or excessive response to an allergen or irritant.

Therefore, "Contact Hypersensitivity" describes a condition where an exaggerated response or allergic reaction occurs when a person's skin comes into contact with a specific substance.