COFACTOR PROTEIN S Meaning and
Definition
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Cofactor Protein S is a term used in biochemistry and molecular biology to describe a specific protein that acts as a cofactor in various enzymatic reactions. It is an essential component in the regulation of blood coagulation and plays a crucial role in the anticoagulant pathway.
Protein S is primarily synthesized in the liver and is secreted into the bloodstream. It circulates as a plasma glycoprotein and can exist in two forms: free protein S and protein S bound to C4b-binding protein. However, when activated protein C cleaves the latter form, it releases free protein S.
Cofactor Protein S acts as an essential cofactor for activated protein C (APC), which is a key enzyme involved in the regulation of blood clotting. When APC binds to Cofactor Protein S, it forms a complex that efficiently inhibits the activities of factors Va and VIIIa, preventing the formation of blood clots. This interaction enhances activated protein C's anticoagulant activity, leading to the inhibition of blood coagulation.
Cofactor Protein S deficiency has been associated with a higher risk of venous thromboembolism, a condition characterized by the formation of blood clots in veins. This deficiency can be inherited or acquired, and it is usually accompanied by an increased risk of developing recurrent thrombosis.
In summary, Cofactor Protein S is a vital component of the anticoagulant pathway, acting as a cofactor for activated protein C. Its role in inhibiting blood clot formation is crucial for maintaining proper blood circulation and preventing thrombotic events.
Common Misspellings for COFACTOR PROTEIN S
- xofactor protein s
- vofactor protein s
- fofactor protein s
- dofactor protein s
- cifactor protein s
- ckfactor protein s
- clfactor protein s
- cpfactor protein s
- c0factor protein s
- c9factor protein s
- codactor protein s
- cocactor protein s
- covactor protein s
- cogactor protein s
- cotactor protein s
- coractor protein s
- cofzctor protein s
- cofsctor protein s
- cofwctor protein s
- cofqctor protein s
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