Chronic Progressive Multiple Sclerosis (CPMS) is a medical condition characterized by the gradual and continuous deterioration of the central nervous system (CNS) over time. It is a specific type of multiple sclerosis (MS) that presents with a progressive course, meaning it worsens steadily without periods of remission or relapse.
In CPMS, the immune system mistakenly attacks the protective covering of nerve fibers, known as the myelin sheath, causing inflammation and subsequent damage to the CNS. This damage disrupts the normal transmission of electrical signals between the brain and the rest of the body, resulting in a wide range of neurological symptoms.
The progression of CPMS symptoms can vary among individuals, but commonly includes muscle weakness or stiffness, loss of coordination and balance, fatigue, numbness or tingling sensations, as well as cognitive impairments such as memory loss and difficulty with concentration. As the condition progresses, individuals may experience difficulties with mobility, fine motor skills, and other bodily functions.
Unlike other forms of MS, such as relapsing-remitting or secondary progressive MS, CPMS does not typically show periods of improvement or remission. This chronic nature and progressive worsening of symptoms can greatly impact a person's quality of life, making it important to manage symptoms and provide appropriate supportive care.
Treatment options for CPMS aim to slow down disease progression, manage symptoms, and improve overall well-being. These may include medication to modify the immune response, physical and occupational therapy to assist with mobility and daily tasks, as well as lifestyle modifications and counseling to address mental and emotional aspects of living with CPMS.
