CHONDROECTODERMAL DYSPLASIAS Meaning and
Definition
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Chondroectodermal dysplasias (CED) are a group of rare genetic disorders that affect the development of the skeleton and skin. This term encompasses multiple conditions that share similar characteristics and are characterized by abnormalities in the growth of cartilage and ectodermal tissues.
CED is typically inherited in an autosomal recessive pattern, which means that both parents must carry a copy of the mutated gene to pass the condition on to their offspring. It is caused by mutations in specific genes involved in the development of connective tissues and embryonic ectoderm. These mutations lead to disruptions in the normal formation of the skeleton, causing skeletal abnormalities such as short stature, abnormal bone growth, and joint deformities.
In addition to skeletal manifestations, individuals with CED also display abnormalities in the skin, teeth, hair, and nails. Skin findings can include dryness, abnormal pigmentation, and increased vulnerability to infections. Dental abnormalities in these individuals often involve missing or malformed teeth, while changes in hair and nails may range from sparse hair and brittle nails to complete absence.
Diagnosis of CED usually involves a physical examination, evaluation of the individual's clinical features, and genetic testing to identify the specific gene mutation. Treatment options for CED are usually supportive and aim to manage the skeletal abnormalities, improve skin health, and address any associated complications. Specialized medical and dental care, along with psychological support, may be necessary to promote quality of life and manage any functional limitations associated with CED.
Common Misspellings for CHONDROECTODERMAL DYSPLASIAS
- xhondroectodermal dysplasias
- vhondroectodermal dysplasias
- fhondroectodermal dysplasias
- dhondroectodermal dysplasias
- cgondroectodermal dysplasias
- cbondroectodermal dysplasias
- cnondroectodermal dysplasias
- cjondroectodermal dysplasias
- cuondroectodermal dysplasias
- cyondroectodermal dysplasias
- chindroectodermal dysplasias
- chkndroectodermal dysplasias
- chlndroectodermal dysplasias
- chpndroectodermal dysplasias
- ch0ndroectodermal dysplasias
- ch9ndroectodermal dysplasias
- chobdroectodermal dysplasias
- chomdroectodermal dysplasias
- chojdroectodermal dysplasias
- chohdroectodermal dysplasias
Etymology of CHONDROECTODERMAL DYSPLASIAS
The term "Chondroectodermal Dysplasias" is a medical term derived from the Greek roots "chondros" meaning "cartilage", "ekto" meaning "outer", "derma" meaning "skin", and "dysplasia" meaning "abnormal growth or development".
"Chondro-" is related to cartilages, which are a type of connective tissue present in the body, providing structural support to various body parts. "Ectoderm" refers to the outermost layer of cells in developing embryos that eventually give rise to the skin, hair, nails, and certain glands. "Dysplasias" indicates abnormal growth or development.
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