AZASERINE Meaning and
Definition
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Azaserine is a synthetic non-proteinogenic amino acid, which is derived from natural compounds found in Streptomyces species of bacteria. It is known for its anticancer properties and is commonly used as a chemotherapeutic agent in cancer research.
Azaserine works by inhibiting the enzyme called glutamine amidotransferase, which is involved in the synthesis of certain essential amino acids, including glutamine and asparagine. By inhibiting this enzyme, azaserine disrupts the growth and proliferation of cancer cells that rely heavily on these amino acids for their survival and replication.
Due to its potent anticancer activity, azaserine has been extensively studied as a potential treatment for various types of cancer, including solid tumors and blood cancers. It has shown promising results in preclinical studies and is often used as a research tool to investigate the mechanisms of cancer development and explore new therapeutic approaches.
However, it is important to note that azaserine is not currently approved for clinical use in humans due to its toxicity and potential side effects. Its use is mainly restricted to laboratory settings and experimental models. Further research and clinical trials are needed to fully understand its therapeutic potential and develop safer and more effective formulations for potential future use in cancer treatment.
Common Misspellings for AZASERINE
Etymology of AZASERINE
The word "Azaserine" is derived from its chemical composition and structure. It is a combination of "aza", which indicates the presence of a nitrogen atom, and "serine", which refers to its structural similarity to the amino acid serine. Azaserine is a synthetic antimetabolite compound that is structurally similar to glutamine, a naturally occurring amino acid.
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