APOPROTEIN C Meaning and
Definition
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Apoprotein C is a term used in biochemistry to refer to a group of proteins that are associated with certain lipoproteins, specifically high-density lipoproteins (HDL). These apoproteins play a vital role in lipid metabolism and transport within the body. Apoprotein C is synthesized in the liver and intestine and subsequently gets incorporated into HDL particles.
The main function of apoprotein C is to facilitate the interaction between HDL and enzymes that are responsible for lipid metabolism. It plays a key role in the activation and regulation of these enzymes, including lipoprotein lipase, hepatic lipase, and phospholipase A2. This enables the efficient breakdown of lipid particles and the release of free fatty acids.
In addition to their enzymatic role, apoprotein C also plays a role in reverse cholesterol transport, a crucial process by which excess cholesterol is removed from peripheral tissues and transported back to the liver for excretion. By interacting with other apoproteins and enzymes, apoprotein C helps promote the efflux of cholesterol from cells and its incorporation into HDL particles, allowing for its efficient transport back to the liver.
Dysfunction or genetic mutations in apoprotein C have been associated with various metabolic disorders, including dyslipidemia, hypertriglyceridemia, and atherosclerosis. Thus, understanding the structure and function of apoprotein C is vital for elucidating the underlying mechanisms involved in lipid metabolism and its implications in various metabolic diseases.
Common Misspellings for APOPROTEIN C
- zpoprotein c
- spoprotein c
- wpoprotein c
- qpoprotein c
- aooprotein c
- aloprotein c
- a-oprotein c
- a0oprotein c
- apiprotein c
- apkprotein c
- aplprotein c
- appprotein c
- ap0protein c
- ap9protein c
- apoorotein c
- apolrotein c
- apo-rotein c
- apo0rotein c
- apopeotein c
- apopdotein c
Etymology of APOPROTEIN C
The term "Apoprotein C" is derived from the combination of two components: "apo" and "protein C".
1. "Apo": The prefix "apo-" is of Greek origin and means "away from" or "without". It is commonly used in biology and medicine to refer to a protein component that is present without its associated prosthetic group or non-peptide molecule necessary for its complete function. In this context, "apo" indicates that the protein is lacking its prosthetic group.
2. "Protein C": The term "protein C" refers to a specific protein in the blood, which, in this case, is referred to in its apoprotein form. Protein C is a vitamin K-dependent protein that plays a vital role in the regulation of blood coagulation.
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